Abstracts, Posters and Video



Videos

January 29, 2016, Chicheley Hall.

Cellular and molecular determinants of the hemodynamic response.

Download slides here

 

 

 

November 4, 2015, USC.

Quantitative microscopic imaging and genetics for investigation of neurodegeneration and mental disease.

 

 

 

 

May 20, 2013, NIH.

Neurovascular Coupling: Noninvasive Imaging Signatures of Microscopic Mechanisms.

 

 

 

 

Abstracts and Posters

Recent

2016 BRAIN Initiative: Microscopic foundation of multimodal human imaging

Uhlirova H, Kılıç K, Tian P, Sakadzic S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yasseen M, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov SA, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A.
BRAIN Initiative investigators meeting 2016

Abstract

Poster

2016 Two-photon microscopy measurement of cerebral metabolic rate of oxygen using periarteriolar oxygen concentration gradients

Sava Sakadzic, Mohammad A. Yaseen, Rajeshwer Jaswal, Emmanuel Roussakis, Anders M. Dale, Richard B. Buxton, Sergei A. Vinogradov, David A. Boas, Anna Devor
Society for Neuroscience Annual Meeting Abstr. 560.17

Abstract

Poster

2016 Enabling widespread use of two-photon phosphorescence lifetime microscopy (2PLM) of oxygen in the brain

Sava Sakadzic, Tatiana V. Esipova, Mohammad A. Yaseen, Anna Devor, Sergei A. Vinogradov, David A. Boas
Society for Neuroscience Annual Meeting Abstr. 560.16

Abstract

Poster

2016 Simulating the light propagation in rodent brain tissues using ray tracing with a 3D microvasculature model

P. Tian, S. Ifeanyi, T.J. Sauer, W. Cotton, A. Devor, Q. Fang, Lana Ruvinskaya, H. Uhlirova, P. A. Saisan, A. M. Dale, D. A. Boas, S. Sakadzic.
Society for Neuroscience Annual Meeting Abstr. 632.19

Abstract

Poster

2016 Neurovascular Network Explorer 2.0: a database of 2-photon single-vessel diameter measurements in response to optogenetic stimulation of inhibitory neurons

Saisan P, Tian P, Kılıç K, Thunemann M, Sridhar VB, Bartsch H, Dale AM, Devor A, Uhlirova H.
Society for Neuroscience Annual Meeting Abstr. 97.01.

Abstract

Poster

2016 Mutlicolor two-photon excitation for increasing fluorescence excitation depth

Yang M-H, Ferri CGL, Saisan P, Abashin M, Tian P, Devor A, Fainman Y.
Society for Neuroscience Annual Meeting Abstr. 270.01.

Abstract

Poster

2016 Vasoconstriction induced by cortical inhibition reduces cerebral blood flow and hemoglobin oxygenation

Desjardins M, Kılıç K, Mateo C, Ferri CGL, Cheng Q, Weldy KL, Kleinfeld D, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr. 319.07.

Abstract

Poster

2016 The selective role of cortical inhibitory interneurons in functional hyperemia

Kılıç K, Uhlirova H, Tian P, Thunemann M, Desjardins M, Saisan PA, Sakadzic S, Ness TV, Mateo C, Cheng Q, Weldy KL, Razoux F, Vandenberghe M, Cremonesi JA, Ferri CG, Nizar K, Sridhar VB, Steed TC, Abashin M, Fainman Y, Masliah E, Djurovic S, Andreassen OA, Silva GA, Boas DA, Kleinfeld D, Buxton RB, Einevoll GT, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr. 319.08.

Abstract

Poster

2016 Two-photon in vivo imaging of neuronal membrane potential with VoltageFluor

Vandenberghe M, Thunemann M, Uhlirova H, Kılıç K, Woodford CR, Ferri CLF, Yang M-H, Tian P, Saisan PA, Abashin M, Cheng Q, Weldy KL, Djurovic S, Andreassen OA, Dale AM, Fainman Y, Einevoll GT, Tsien RY, Devor A.
Society for Neuroscience Annual Meeting Abstr. 468.06.

Abstract

Poster

Poster Archive

2014 Large Arteriolar Component of Oxygen Delivery Implies Safe Margin of Oxygen Supply to Cerebral Tissue

Sava Sakadzic, Emiri T. Mandeville, Louis Gagnon, Joseph J. Musacchia, Mohammad A. Yaseen, Meryem A Yucel, Joel Lefebvre, Frederic Lesage, Anders M. Dale, Katharina Ekermann-Haerter, Cenk Ayata, Vivek J. Srinivasan, Eng H. Lo, Anna Devor, David A. Boas
Society for Neuroscience Annual Meeting Abstr. 590.29

Abstract

Poster

2014 Functional imaging of human iPSCs-derived neurons integrated in mouse cortex using 2-photon microscopy in vivo

Cleber A. Trujillo, Hana Uhlirova, Kivilcim Kılıç, Payam A. Saisan, Qun Cheng, Kimberly L. Weldy, Anders M. Dale, Alysson R. Muotri, Anna Devor.
Society for Neuroscience Annual Meeting Abstr. 590.29

Abstract

Poster

2014 Evidence for the breakdown of neurotransmitter integration pathways in schizophrenia

Anna Devor, Wesley K. Thompson, Yunpeng Wang, Per Svenningsson, Andrew J. Schork, Verena Zuber, Chi-Hua Chen, Srdjan Djurovic, Rahul S. Desikan, Linda K. McEvoy, Ole A. Andreassen, Anders M. Dale.
Society for Neuroscience Annual Meeting Abstr. 424.07

Abstract

Poster

2014 Cortical inhibitory interneurons shape functional hyperemia

Hana Uhlirova, Kivilcim Kılıç, Peifang Tian, Payam A. Saisan, Qun Cheng, Florence Razoux, Kimberly L. Weldy, Eliezer Masliah, David A. Boas, Anders M. Dale, Anna Devor.
Society for Neuroscience Annual Meeting Abstr. 352.10

Abstract

Poster

2014 The role of nNOS for hyperemia induced by sensory and optogenetic stimulation in vivo

Peifang Tian, Hana Uhlirova, Kivilcim Kılıç, Payam A. Saisan, Qun Cheng, Kimberly L. Weldy, Eliezer Masliah, David A. Boas, Anders M. Dale, Anna Devor.
Society for Neuroscience Annual Meeting Abstr. 352.11

Abstract

Poster

2014 Simulating the light propagation in brain tissues using ray tracing with a dynamic and heterogeneous tissue model

Thomas J. Sauer, Peifang Tian, Anna Devor, Qianqian Fang, Hana Uhlirova, Payam A. Saisan, Anders M. Dale, David A. Boas, Sava Sakadzic.
Society for Neuroscience Annual Meeting Abstr. 185.27

Abstract

Poster

2013 Modeling BOLD-fMRI on real vascular stacks measured with two-photon microscopy during functional activation

Louis Gagnon, Sava Sakadzic, Frédéric Lesage, Joseph J. Musacchia, Joel Lefebvre, Qianqian Fang, Meryem A. Yucel, Karleyton C. Evans, Emiri T. Mandeville, Julien Cohen-Adad, Jonathan R. Polimeni, Mohammad A. Yaseen, Eng H. Lo, Douglas N Greve, Richard B. Buxton, Anders M. Dale, Anna Devor, David A. Boas.
Society for Neuroscience Annual Meeting Abstr. 103.14

Abstract

Poster

2013 Modeling the BOLD signal at the microscopic level using quantitative optical microscopy measurements

Gagnon L, Sakadzic S, Devor A, Fang Q, Lesage F, Srinivasan VJ, Mandeville ET, Lo EH, Yaseen MA, Roussakis E, Vinogradov SA, Buxton BR, Dale AM, Boas DA.
ISMRM Annual Meeting.

Abstract

2012 In vivo profiling of astrocytic calcium excitability and downstream vascular effects: Fluorescence intensity and lifetime measurements

H. UHLIROVA, P. A. SAISAN, E. S. NORHEIM,4, Q. CHENG, K. L. WELDY, S. L. GRATIY, G. T. EINEVOLL, A. M. DALE, A. DEVOR.
Society for Neuroscience Annual Meeting Abstr. 590.12.

Abstract

Poster

2012 Spatial gradient of vasodilation kinetics in the mouse somatosensory cortex

P. TIAN, H. UHLIROVA, Q. CHENG, K. L. WELDY, P. A. SAISAN, K. NIZAR, T. C. STEED, V. B. SRIDHAR, G. A. SILVA, A. M. DALE, A. DEVOR.
Society for Neuroscience Annual Meeting Abstr. 590.16.

Abstract

Poster

2012 Novel heteroaromatic organic compound normalized calcium abnormalities in α-synuclein transgenic Parkinson Disease-like mice model in vivo

L. REZNICHENKO, Q. CHENG, M. MANTE, P. A. SAISAN, E. M. ROCKENSTEIN, C. R. OVERK, I. F. TSIGELNY, W. WRASIDLO, D. L. PRICE, A. M. DALE, A. DEVOR, E. MASLIAH.
Society for Neuroscience Annual Meeting Abstr. 53.25.

Abstract

Poster

2012 Two-photon microscopy of oxygen distributions in mouse cerebral microvasculature

S. SAKADZIC, E. T. MANDEVILLE, A. DEVOR, M. A. YASEEN, J. J. MUSACCHIA, L. GAGNON, K. EIKERMANN-HAERTER, E. ROUSSAKIS, V. J. SRINIVASAN, C. AYATA, E. H. LO, A. M. DALE, S. A. VINOGRADOV, D. A. BOAS.
Society for Neuroscience Annual Meeting Abstr. 95.12.

Abstract

Poster

2012 Investigating laminar specificity of neurovascular coupling using OCT angiography

V. J. SRINIVASAN, A. DEVOR, H. RADHAKRISHNAN, D. A. BOAS, M. FRANCESCHINI.
Society for Neuroscience Annual Meeting Abstr. 927.14.

Abstract

2012 Computation of baseline flow across the mouse cortex using two-photon microscopy and vascular anatomical network modeling

Gagnon L, Mandeville ET, Yaseen MA, Srinivasan VJ, Lo EH, Roussakis E, Vinogradov SA, Devor A, Boas DA, Sakadzic S.
OSA Annual Meeting.

Abstract

2010 Direct and simultaneous 2-photon imaging of intravascular and tissue oxygenation during the response to sensory stimulation in vivo

Devor A, Sakadzic S, Yaseen MA., Roussakis E, Srinivasan VJ, Dale AM, Vinogradov SA., Boas DA.
Society for Neuroscience Annual Meeting Abstr. 192.6.

Abstract

Poster

2010 Two-photon microscopic measurement of distribution and cerebral metabolic rate of oxygen in cortical tissue

Sakadzic S, Devor A, Yaseen MA., Roussakis E, Srinivasan VJ, Vinogradov SA., Boas DA.
Society for Neuroscience Annual Meeting Abstr. 192.7.

Abstract

Poster

2010 Unreliable and delayed astrocytic calcium response does not support the hypothesis of calcium-dependent astrocytic regulation of blood flow

Nizar KW, Reznichenko L, Cheng Q, Sakadzic S, Boas DA, Masliah E, Dale AM, Silva GA, Devor A.
Society for Neuroscience Annual Meeting Abstr. 192.9.

Abstract

Poster

2010 Estimation of synaptic currents from laminar multi-electrode recordings

Gratiy SL, Devor A, Einevoll GT, Dale AM.
Society for Neuroscience Annual Meeting Abstr. 820.8.

Abstract

Poster

2010 In vivo study of abnormal neuronal Ca2+ activity in α-synuclein transgenic mice model of Parkinson’s disease using 2-photon microscopy

Reznichenko L, Nizar KW, Cheng Q, Devor A, Masliah E.
Society for Neuroscience Annual Meeting Abstr. 192.15.

Abstract

Poster

2010 Direct and simultaneous 2-photon imaging of intravascular and tissue oxygenation during the response to sensory stimulation in vivo

Devor A, Sakadzic S, Saisan PA, Yaseen MA, Roussakis E, Tian P, Srinivasan VJ, Dale AM, Vinogradov SA, Boas DA.
Gordon Research Conference on Cerebral Blood Flow and Metabolism. Proctor Academy, NH.

Abstract

Poster

2010 Delayed and infrequent astrocytic calcium response does not support the hypothesis of calcium-dependent astrocytic triggering of vasodilation

Nizar K, Tian P, Cheng Q, Saisan PA, Steed TC, Sridhar VB, MacDonald CL, Reznichenko L, Sakadzic S, Boas DA, Masliah E, Dale AM, Silva GA, Devor A.
Gordon Research Conference on Cerebral Blood Flow and Metabolism. Proctor Academy, NH.

Abstract

Poster

2009 Monte Carlo simulation of spatial resolution and penetration depth of two dimensional optical imaging methods

Tian P, Devor A, Dale AM, Boas D.A.
Society for Neuroscience Annual Meeting Abstr. 687.11.

Abstract

Poster

2009 Joint modeling of voltage-sensitive imaging data and laminar microelectrode recordings

Linden H, Pettersen K.H, Devor A, Tian P, Teng IC, Dale AM, Einevoll G.T.
Society for Neuroscience Annual Meeting Abstr. 656.10.

Abstract

Poster

2009 In vivo calcium imaging in α-synuclein transgenic model of Parkinson’s disease

Masliah E, Tian P, Teng IC, Rockenstein E, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr. 698.10.

Abstract

2009 From two-photon microscopy to fMRI: BOLD transients as a function of single-vessel dilation and constriction

Buxton R, Tian P, Teng IC, Lu K, Scadeng M, May LD, Kurz R, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr. 670.7.

Abstract

Poster

2009 In vivo functional NADH imaging with single-cell resolution

Devor A, Sakadzic S, Yucel MA, Teng IC, Kasischke KA, Boas DA.
Society for Neuroscience Annual Meeting Abstr. 672.10.

Abstract

Poster

2009 From two-photon microscopy to BOLD-fMRI: association of an undershoot of arteriolar diameter with the BOLD post-stimulus undershoot

Devor A, Buxton R, Tian P, Teng I, Lu K, May L, Kurz R, Dale A.
ISMRM Annual Meeting

Abstract

2008 In vivo two-photon measurement of single vessel diameter changes using astrocytic indicator SR101

Teng IC, Tian P, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr, 286.3.

Poster

2008 Characterization of the spatiotemporal responses of surface and penetrating cerebral arterioles using two-photon microscopy

Tian P, Teng IC, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr, 286.5.

Poster

2008 Characterization of the spatiotemporal responses of surface and penetrating cerebral arterioles using two-photon microscopy

Tian P, Teng IC, Dale AM, Devor A.
Gordon Research Conference on Cerebral Blood Flow and Metabolism. Proctor Academy, NH.

Poster

2008 Spatiotemporal brain imaging: microscopic & systems level

BRP Annual Meeting, Bethesda, NIH.

Poster

2007 Three dimentional vascular anatomical model of oxygen delivery

Boas DA, Sakadzic S, Shalinsky M, Jones SR, Devor A, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 87.2.

Poster

2007 Hemodynamic augmentation in response to a paired whisker stimulus as a function of cortical distance

Tian P, Teng IC, Dunn AK, Boas DA, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr, 87.6.

Poster

2007 Analysis of vascular diameter and velocity of blood flow using two-photon laser scanning microcopy (TPLSM) data

Teng IC, Devor A, Tian P, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 87.6.

Poster

2007 Spatiotemporal brain imaging: microscopic & systems level

BRP Annual Meeting, Bethesda, NIH.

Poster

2006 Applying optical imaging to study neurovascular coupling in cerebral cortex: from populational scale to single-cell single-vessel measurements

Devor A, Hillman EMC, Nishimura N, Ulbert I, Narayanan S, Teng I, Dunn AK, Boas DA, Kleinfeld D, Dale AM.
Biomedical Optics Meeting (Biomed 2006).

Abstract

2006 Estimation of cortical microcircuit model from joint thalamic single-unit and cortical laminar electrode recordings in rat whisker-barrel system

Blomquist P, Indahl UG, Devor A, Ulbert I, Einevoll G, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 53.23.

Poster

2006 Spatiotemporal profile of single-vessel hemodynamic response to a somatosensory stimulus in relation to maps of underlying neuronal activity

Tian P, Devor A, Nishimura N, Teng IC, Dale AM, Kleinfeld D.
Society for Neuroscience Annual Meeting Abstr, 363.6.

Poster

2006 Vascular compartment separation using optical spectroscopy and BOLD fMRI in rat barrel cortex

Hillman EMC, de Crespigny AJ, D’Arceuil HE, Mandeville JB, Marota JJ, Teng IC, Dale AM, Boas DA, Devor A.
Society for Neuroscience Annual Meeting Abstr, 261.11.

Poster

2006 Neurovascular coupling in a rat model of ischemic stroke recovery

Devor A, Hillman EMC, Kim Y, Zhu H, Moore JB, Narayanan S, Lo EH, Rosen BR, Dale AM, Boas DA.
Society for Neuroscience Annual Meeting Abstr, 261.8.

Poster

2006 Neurovascular coupling during contra- and ipsilateral somatosensory stimulation in rat SI

Boas DA, Hillman EMC, Kim Y, Narayanan S, Zhu H, Waeber C, Haslinger RH, Lo EH, Rosen BR, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr, 261.9.

Poster

2005 Spatial neurovascular coupling as revealed by full-field neuronal and hemodynamic imaging

Devor A, Boas DA, Ulbert I, Narayanan S, Jones PB, Hillman EMC, Dunn AK, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 456.11.

Poster

2005 A spatial-temporal analysis of neuron-vascular coupling during evoked responses in rat somatosensory cortex

Jones SR, Devor A, Dunn AK, Hillman EMC, Narayanan S, Ulbert I, Dale AM, Boas DA.
Society for Neuroscience Annual Meeting Abstr, 454.9.

Poster

2005 Spatially distributed balloon model of the cerebral vascular response to brain activation

Boas DA, Devor A, Jones SR, Dunn AK, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 454.2.

Poster

2005 Resolving the roles of vascular compartments during functional activation: a high-resolution 3D optical imaging study

Hillman EMC, Devor A, Dunn AK, Skoch J, Bacskai BJ, Dale AM, Boas DA.
Society for Neuroscience Annual Meeting Abstr, 189.12.

Poster

2005 Laminar analysis of trial-to-trial variability in somatosensory cortex

Haslinger RH, Ulbert I, Brown EN, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr, 984.18.

Poster

2005 Contrasting voltage-sensitive dyes imaging with depth-resolved neuronal activity in rat somatosensory cortex

Ulbert I, Narayanan S, Dale AM, Devor A.
Society for Neuroscience Annual Meeting Abstr, 457.5.

Poster

2005 Spatiotemporal brain imaging: microscopic & systems level

BRP Annual Meeting, Bethesda, NIH.

Poster

2004 Coupling of cortical hemodynamic response to neural activity in cortex and thalamus

Devor A, Ulbert I, Dunn AK, Narayanan S, Andermann ML, Boas DA, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 642.11.

Poster

2004 Coupling of cortical hemodynamic response to neural activity in cortex and thalamus

Devor A, Ulbert I, Dunn AK, Narayanan S, Andermann ML, Jones SR, Boas DA, Dale AM.
Gordon Research Conference on Cerebral Blood Flow and Metabolism. Colby College, Waterville, ME.

Poster

2004 Physiologically constrained population modeling of cortical activity in rat barrel cortex measured with laminar electrodes

Einevoll G, Devor A, Ulbert I, Kermit M, Halgren E, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 921.13.

Poster

2004 Spatiotemporal brain imaging: microscopic & systems level

BRP Annual Meeting, Bethesda, NIH.

Poster

2003 Parallel fiber beams produce a strong excitatory effect on Purkinje cells along the beam only under direct electrical stimulation

Devor A, Dale AM, Dunn AK, Narayanan S, Ulbert I, Boas DA, Bower JM.
Society for Neuroscience Annual Meeting Abstr, 75.3.

Poster

2003 Dynamic imaging of brain function: relating imaging signals to underlying physiology

Devor A, Dunn AK, Andermann ML, Ulbert I, Narayanan S, Jones SR, Einevoll G, Bower JM, Boas DA, Dale AM.
12th Annual Meeting of Israel Society for Neuroscience. Neural Plasticity 10 (3): 192.

Abstract

2003 Spatial temporal properties of neurovascular coupling

Jones SR, Devor A, Dunn AK, Boas DA, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 692.1.

Poster

2002 Coupling of hemodynamic and neuronal activity in rat somatosensory cortex

Devor A, Andermann ML, Dunn AK, Ulbert I, Boas DA, Dale AM.
Society for Neuroscience Annual Meeting Abstr, 651.4.

Poster

2002 Coherence of subthreshold oscillations in coupled inferior olivary neurons

Devor A, Yarom Y.
Cerebellum: recent developments in cerebellar research Annals of the New York Academy of Sciences, 978: 508.

Poster

2001 Properties of electrotonic coupling in inferior olivary network

Devor A, Yarom Y.
Society for Neuroscience Annual Meeting Abstr, 27 (1): 183.

Poster